FUNDAMENTAL STUDIES ON THE LUNG TRANSPLANTATION

Translational Insights on Lung Transplantation: Learning from Immunology

The introduction of ex vivo lung perfusion (EVLP) in the practice of lung transplantation has allowed the reconditioning of the marginal grafts and their conversion into transplantable grafts. In addition, EVLP can provide a platform for the application of various preventive measures to decrease the incidence of post-transplant complications. While the Toronto team targets the attenuation of th...

Studies on Organ Transplantation

Seven autoplastic transplantations and one homoplastic transplantation of the spleen of dogs were made. One autotransplantation was successful, the gland being normal at the end of 88 days.

On the horizon: neonatal lung transplantation.

There are several congenital lung lesions that result in severe pulmonary hypoplasia and neonatal death. These malformations include congenital diaphragmatic hernia (CDH), oligohydramnios induced pulmonary hypoplasia, and congenital cystic adenomatoid malformation of the lung. Severely affected newborns are not salvageable by current surgical techniques or medical treatment, although one new ex...

Studies on the immunogenic properties of La Sota NDV propagated in embryo lung primary cells culture

Studies on the Kinetics of Transplantation Immunity1

Using the parameter of the number of tumor cells necessary to produce s.c. tumors in allogeneic animals at varying intervals after antigenic stimulation, immunity was found to be in force as early as 2 days after primary antigenic stimulation. It reached a peak at 8-10 days and had largely subsided by the end of a month. This method was also applied to the quantitative study of the onset, degre...